Deficiencia de vitamina D y de hierro en niños y adolescentes con parálisis cerebral

Resumen

Introduction: Children and adolescents with cerebral palsy (CP) are at a greater risk of mal-nutrition and micronutrient deficiencies. Two deficiencies that we can study and treat arevitamin D (VD) and iron deficiencies; however, no studies have described these deficiencies inChile.Objective: To describe the status of VD and iron in patients with CP and evaluate the rela-tionship with certain factors associated with deficiencies of these micronutrients.Patients and method:We performed a descriptive, cross-sectional study including 69 patientsaged between 2 and 21 years, from two public hospitals. Data were obtained on demographicvariables, motor function, use of feeding tube, and pharmacological treatment. We perfor-med a nutritional assessment according to patterns of CP and determined 25-hydroxyvitamin D(25[OH]D) ferritin, and albumin levels.Results: Patients’ mean age was 11.1 ± 4.9 years; 43 (62.3%) were male; and 56 (81.2%) hadmoderate-to-severe CP. Thirty-five (50.7%) used a nasogastric tube and/or gastrostomy; 15.4%were underweight and 73.8% were eutrophic, all with normal height. Twenty (29%) and 4 patients(6.2%) received VD and iron supplementation, respectively. Albuminaemia was normal in allpatients. Mean 25(OH)D level was 24.3 ± 8.8 ng/mL; 33 patients (47.8%) had insufficiency and21 (30.4%) deficiency; 36 patients (52.2%) had low ferritin levels. There was no associationbetween 25(OH)D level and the other variables studied. Low ferritin levels were found to beassociated with older age (P = .03), being male (P = .006), and feeding tube use (P = .006).Conclusions: The patients studied mainly had moderate-to-severe CP, with a high frequencyof suboptimal VD values and low plasma ferritin; few patients received VD and/or iron supple-mentation. We suggest monitoring 25(OH)D and ferritin levels due to the high rate of deficiencyof these nutrients; public hospitals should be equipped with drugs to treat these deficiencies.

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Cómo citar (APA 7)

Le Roy, C., Barja, S., Sepúlveda, C., Guzmán, M. L., Olivarez, M., Figueroa, M. J., & Álvarez, M. (2021). Deficiencia de vitamina D y de hierro en niños y adolescentes con parálisis cerebral. Neurología. https://doi.org/10.1016/j.nrl.2017.11.005